First, please discuss everything with your vet. Caring
for a dog with cancer must be teamwork. If you’re working with a holistic veterinarian, then
perhaps a lot of this information is already known to him/her; that saves a
step. If you’re working with your regular vet, you may have to educate
him/her to some new ideas. Most vets are totally open to learning about new
ways of treating an old enemy so don’t hesitate to open discussions.
Any surgical procedures that are available should be
used to remove primary tumors since it is the primary tumor that can send out
seeds for metastasis. Other cancers like leukemia, lymphoma and hemangiosarcoma
are usually cancers of the blood, lymph system or blood vessels, which make
it more difficult to locate and remove a primary growth. In these cases, it’s
probably not going to be operable but that does not translate to hopeless.
Current research points to a simple fact that cancer has many names but only
one cause--a breakdown of the naturally occurring process of APOPTOSIS.
Apoptosis is genetic program in all of us and our pets
that signals cells when it’s their time to go. Apoptosis is regulated by the P53 tumor suppressor
gene (the gene has been directly linked to osteosarcoma and hemangiosarcoma
in studies done with Rottweilers). A mutation occurs in this process that allows
mutant cells to grow out of control and that is cancer. The different names
of cancers are usually given to the type of tissue, area of the body, or system
that harbors the mutant cells. For example, mast cell cancer forms from mast
cells which are naturally occurring cells in the body, spindle cell carcinoma
derives from naturally occurring spindle cells etc. I’m making this as
simple as possible but it is far more complex in reality.
People and animals are born with a genetic predisposition
or flaw in their DNA that allows a “trigger” to set in motion the failure of apoptosis.
The trigger can be a failure to provide the right nutrients, or an inability
to absorb one or more nutrients. Triggers are environmental—exposure to
a toxin through inhalation, absorption or direct contact. Triggers can
be a combination of all of these and more. Scientists are just beginning to
understand these mechanisms.
In addition to the many chemotherapeutic drugs available, there are alternative
therapies that do not cause serious or fatal side effects. Most of these are
too new to say with certainty that they work for all animals with all forms
of cancer but they are well worth using either alone or as an adjunct to chemotherapy.
Again, discuss this with your vet.
Because the Internet is such an evolving world that changes from day to day,
your best sources for these products is to use Google and do a search or call
me at 805-991-7449. Here are a few of the more promising alternatives:
Beta Glucan Supreme
For decades, the word was out that something in cruciferous vegetables protects
animals from cancer; in 1992, scientists from Johns Hopkins University identified
the active constituent as a chemical called sulforaphane. Broccoli contains
more sulforaphane than the other vegetables. The best source of it comes from
sprouts that have grown to the second leaf stage; these seedlings contain between
10 to 100 times as much sulforaphane as a full-grown broccoli.
To date the sulforaphane research focusing on cancer has discovered that
this protection results from stimulation of the body's own antioxidant
and detoxification system, which is comprised of what scientists call Phase
2 Enzymes. The enzymes eliminate carcinogens from the body before they can
cause DNA damage. This action protects healthy cells from cancer triggering
More exciting from a cutting edge point of view is a
paper in the March 2000 issue of Cancer Research which reported for the first
time that sulforaphane can cause cancer cells to self-destruct, that it triggers
programmed cell death or apoptosis. Research that is more recent reports on
the genetic mechanisms by which these broccoli chemicals work. For example,
a recent study on breast cancer showed sulforaphane binding to mammary tissue
after just a single dose of broccoli sprouts. Earlier studies from 1997 and
2000 demonstrated that sulforaphane prevented carcinogens from triggering cancer
in breast tissue. Other benefits of this supplement include increasing the
liver’s capacity to detoxify
potential carcinogens. Sulforaphane glucosinolate is the precursor of
sulforaphane and Beta Glucan Supreme contains sulforaphane glucosinolate (SGS).
Great Life Pet Products formulates their dog foods with Broccoli, Kale, Barley
and Fenugreek sprouts for added protection against cancer.
Neoplasene is an exciting and very effective treatment available from Buck
Mountain Botanicals. There are many people who use this topically for external
growths and have seen some miracles, and as an oral treatment it works this
way: A small amount is ingested with food twice a day. It circulates within
the bloodstream and attacks and kills the mutant cells wherever it finds them.
It takes over and induces apoptosis. Where the genetic program has broken down,
Neoplasene takes its place. There is some controversy over its use because it
is very powerful but it is also very effective. You need to contact Dr. Terence
Fox at Buck Mountain Botanicals to discuss its use and dosage since it is his
treatment protocol. His phone number is 1-406-232-1185.
The key to giving Neoplasene is to prep the stomach because
it will induce vomiting—it is an emetic. The vomiting is not terrible but it’s
not going to help treat the cancer so prepping the stomach is vital. You
must also make certain a large amount of food and water is present to make
the Neoplasene absorbable.
Avemar is derived from fermented wheat germ; it comes in
packets. For dogs, you can add it to yogurt or put it into capsules. Make sure you provide lots of water to dilute the Avemar. Results
of studies show it greatly improves survival and quality of life. There
are no gastric side effects with the exception of a possible soft stool
periodically; but with Avemar, there is no fear of intestinal necrosis.
Avemar is an immune modulator which is important for overall health.
We know that cancer is also an immune system failure.
The next effective treatment is Artemisinin (Arte) which is an extract from
the wormwood plant. Arte is used successfully to treat malaria throughout the
Cancer cells have the highest concentration of iron in their cells because
they need that iron to stimulate growth, get a good blood supply going and eventually
kill the host! Arte attacks cells with the highest concentration of iron much
like the malaria parasite which also contains a lot of iron.
An article appearing in Life Sciences in 2001 by Drs. Singh and Lai at the
University of Washington detailed the rapid and complete destruction of a radiation-resistant
breast cancer cell line in vitro. The destruction occurred within 8 hours and
had little effect on normal cells.
Artemisinin has two semi-synthetic derivatives: Artesunate and Artemether.
A paper published in Oncology in 2001 described the cytotoxic effects of Artesunate
against a wide variety of cancers including melanomas, breast, ovarian, leukemia
and colon cancers. The growth of all of these cancers was inhibited by 50%.
A source for this combination of Arte and its derivatives is Wellcare Pharmaceutical
The source for the high quality Arte used at Washington State University is
Arte must be given on an empty stomach. Allow at least 3 hours to elapse after
feeding and then give the Arte; wait one hour before feeding again. Holley Phamaceutical
will advise you on dosage. Using fat helps with absorption, therefore, give
the capsules with some wild caught salmon oil gelcaps in organic butter or frozen
IP6 with INOSITOL
As mentioned above in the discussion on Arte, tumor cells utilize iron as
a growth factor. Researchers are constantly searching for a drug that would
be able to attach to iron molecules and remove them from the body, producing
an effective anti-cancer drug, without harming the patient. The chemotherapy
drug, Adriamycin (doxorubicin), is an iron binder, but comes with severe side
effects, including heart damage.
There is a naturally occurring compound that chelates (attaches to) iron without
side effects. Inositol hexaphosphate (IP6), is found naturally in seeds and
bran; it selectively removes iron from abnormal cells without side effects.
Dr. Charles Loops, a renowned veterinary homeopathic uses cell salts and nosodes
in his cancer protocol. The aim with homeopathy is to do no harm whatever
decisions you make. http://www.charlesloopsdvm.com/
Supplements that have shown benefits include:
Turkey Tail mushroom
A plant based digestive enzyme
Good Nutrition is needed: Great Life Performance Pet Products makes KrunCheros
dog food and a line of grain and potato free treats with immune boosters such
as: acai berries, goji berries, mangosteen, sprouted chia in their very tasty
The goal in fighting cancer is to make your beloved friend as comfortable
as possible and prolong life; so remember, as long as there is life, there is
hope. Stress is very damaging to all cancer patients so you are encouraged to
keep a very positive attitude in the presence of your pet. They are so in tune
with our body language, our moods and our thoughts, that your stress is their
stress! Why waste your time on feeling negative as long as your pet is there
with you, you are winning the war.
For additional information:
Dr. Elliott at 1-805-991-7449